![]() ![]() These events can occur at any time during use and without warning symptoms. NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. Diclofenac sodium is contraindicated in the setting of coronary artery bypass graft surgery. This risk may occur early in treatment and may increase with duration of use. NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. Topical application route (Gel/Jelly Solution) Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events. ![]() Diclofenac epolamine is contraindicated in the setting of coronary artery bypass graft surgery. Topical application route (Patch, Extended Release) ![]()
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